![]() ![]() large multi-site RCT).Įvidence obtained from well-designed controlled trials without randomization (i.e. These decisions gives the "grade (or strength) of recommendation."Įvidence from a systematic review or meta-analysis of all relevant RCTs (randomized controlled trial) or evidence-based clinical practice guidelines based on systematic reviews of RCTs or three or more RCTs of good quality that have similar results.Įvidence obtained from at least one well-designed RCT (e.g. ![]() Levels of evidence (sometimes called hierarchy of evidence) are assigned to studies based on the methodological quality of their design, validity, and applicability to patient care.
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